Question

when would you pretreat a stained shirt?
after the stain has come out
before putting it in the washing machine

Explanation:

Pretreating a stained shirt is done to loosen and break - down the stain before the main wash. Washing machines may not be able to remove tough stains without pretreatment. So, it should be done before putting the shirt in the washing machine.

Answer:

before putting it in the washing machine