QUESTION IMAGE
Question
- what is the function of memory b cells?
a) kill infected cells
b) initiate the complement cascade
c) provide a rapid immune response during subsequent exposures
d) neutralize toxins directly
- what happens in a positive result in the complement fixation test?
a) sheep red blood cells are lysed
b) no lysis of sheep red blood cells occurs
c) complement is degraded
d) a colored product is formed
- which of the following diagnostic tests involves the use of fluorescent dyes?
a) elisa
b) agglutination test
c) precipitin ring test
d) fluorescent antibody test
Brief Explanations
- Question 5: Memory B cells are part of the adaptive immune system. Their key role is to "remember" a pathogen. When the body is re - exposed to the same pathogen, memory B cells quickly differentiate into plasma cells (which produce antibodies) or more memory B cells, leading to a rapid immune response.
- Option a: Killing infected cells is mainly the function of cytotoxic T cells (not memory B cells).
- Option b: Initiating the complement cascade can be done by antibodies (in the classical pathway) or other molecules (in alternative or lectin pathways), not a direct function of memory B cells.
- Option d: Neutralizing toxins directly is more of a function of antibodies (produced by plasma cells, which can be derived from memory B cells, but not the direct function of memory B cells themselves).
- Question 6: In the complement fixation test, if there is a positive result (i.e., the complement has been "fixed" by the antigen - antibody complex in the test system), there is no complement left to lyse the sheep red blood cells (which are added as an indicator).
- Option a: Sheep red blood cells are lysed in a negative complement fixation test (when complement is not fixed by the test antigen - antibody complex and can then act on the sheep red blood cells).
- Option c: Complement is not degraded in the sense described in the context of a positive test result; it is used up (fixed) in the antigen - antibody - complement interaction.
- Option d: A colored product formation is not a characteristic of the complement fixation test result readout.
- Question 7: The fluorescent antibody test uses fluorescent dyes. These dyes are conjugated to antibodies, and when the antibody binds to its target antigen (in a sample, such as on a slide), the fluorescence can be visualized under a fluorescence microscope.
- Option a: ELISA (Enzyme - Linked Immunosorbent Assay) uses enzymes (not fluorescent dyes) to produce a color change (usually via a substrate - enzyme reaction).
- Option b: Agglutination tests rely on the clumping (agglutination) of particles (like cells or latex beads) coated with antigens or antibodies, not fluorescent dyes.
- Option c: The precipitin ring test is based on the formation of a precipitation ring between antigen and antibody in a gel - like medium, not involving fluorescent dyes.
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- c) Provide a rapid immune response during subsequent exposures
- b) No lysis of sheep red blood cells occurs
- d) Fluorescent antibody test