Question

question 1
which of the following best defines the term pharmacokinetics?
the study of the biological and therapeutic effects of drugs
the study of drugs mechanisms of action
the study of absorption, distribution, metabolism, excretion of drugs in the body
the study and research of new drug development
question 2
which of the following choices are factors that affect the absorption of medications? (select all that apply)
the first - pass effect
the ph in the stomach
the route of administration
the patients kidney function
the presence of food in the stomach
protein binding

Explanation:

Question 1

Pharmacokinetics specifically focuses on how the body processes drugs, which includes absorption, distribution, metabolism, and excretion. The first option refers to pharmacodynamics (effects of drugs). The second is about mechanism of action (not pharmacokinetics). The fourth is drug development research.

• The first - pass effect: Affects absorption as drugs may be metabolized before reaching systemic circulation.
• The pH in the stomach: Can influence the solubility and thus absorption of some drugs.
• The route of administration: Different routes (e.g., oral, intravenous) have different absorption rates and extents.
• The presence of food in the stomach: Can either enhance or inhibit absorption of certain medications.
• The patient's kidney function: Affects excretion (not absorption).
• Protein binding: Affects distribution (not absorption).

Answer:

the study of absorption, distribution, metabolism, excretion of drugs in the body

Question 2