Question

question 6
1 pts
what is the primary pathophysiological
difference between type 1 and type 2
diabetes?

type 1 requires insulin; type 2 does not

type 1 is autoimmune beta cell destruction; type
2 is insulin resistance plus insufficient insulin
production

type 1 affects children; type 2 affects adults

type 1 causes weight loss; type 2 causes weight
gain

question 7
1 pts
what is the relationship between chronic
kidney disease and diabetes?

kidney disease always causes diabetes

ckd is reversible with good glucose control

kidney disease only develops 20+ years after
diabetes onset

diabetes and hypertension cause two-thirds of
ckd cases, and ckd can worsen diabetes control

Explanation:

• Question 6:
• Type 1 diabetes is an autoimmune disease where beta cells in the pancreas are destroyed, leading to little or no insulin production.
• Type 2 diabetes involves insulin resistance (cells don't respond well to insulin) and insufficient insulin production over time.
• The first option about insulin requirement is a treatment aspect, not the primary pathophysiological difference.
• The third option about age - affected groups is a general trend but not the core pathophysiological difference.
• The fourth option about weight changes is a possible symptom, not the primary pathophysiological difference.
• Question 7:
• Kidney disease does not always cause diabetes.
• CKD (Chronic Kidney Disease) is not reversible with good glucose control (it can be managed but not reversed).
• Kidney disease can develop earlier than 20+ years after diabetes onset.
• Diabetes and hypertension are major causes of CKD (two - thirds of cases), and CKD can worsen diabetes control due to issues like fluid and electrolyte imbalances affecting glucose metabolism.

Answer:

• Question 6: Type 1 is autoimmune beta cell destruction; Type 2 is insulin resistance plus insufficient insulin production.
• Question 7: Diabetes and hypertension cause two - thirds of CKD cases, and CKD can worsen diabetes control.