Question

question 4 (mandatory) (1.25 points) a toxin that prevents the hydrolysis of gtp to gdp would have which effect on a g protein signaling pathway? the g protein would remain inactive, and no signal would be transduced. the g protein would remain active, leading to a prolonged cellular response. the g protein would be permanently dissociated from the receptor. the pathway would become dependent on atp instead of gtp.

Explanation:

G - proteins are activated when they bind GTP and inactivate when GTP is hydrolyzed to GDP. If a toxin prevents GTP hydrolysis, G - protein remains bound to GTP (active), leading to a prolonged cellular response. Other options are incorrect: first option says it remains inactive (wrong), third is about dissociation (not related to GTP hydrolysis), fourth is about ATP (G - protein uses GTP, not ATP).

Answer:

The G protein would remain active, leading to a prolonged cellular response.