Question

put it all together: (remember to follow the steps provided in your notes)
the following segment of dna was extracted from the gametes of a gorilla.
original: tta- gcg- act- tat
mutated: tta- ggg- act- tat
which of the following applies to this mutation?

• this mutation is genotypic because the amino acid changed
• this mutation is phenotypic because there was a change in the dna sequence
• this mutation is genotypic because it is in a gamete
• this mutation is phenotypic because the amino acid changed

Explanation:

1. First, recall definitions: Genotype refers to the genetic makeup (DNA sequence), phenotype to observable traits (from proteins/amino acids).
2. Analyze the mutation: The DNA sequence changed (Original: TTA - GCG - ACT - TAT; Mutated: TTA - GGG - ACT - TAT), so it's a genotypic change (affecting DNA, genotype).
3. Evaluate options:

• Option 1: "This mutation is genotypic because the amino acid changed" – Wait, but first, check if amino acid changed. Let's transcribe (simplified: DNA triplet to amino acid, though full process is transcription/translation, but for triplet GCG vs GGG: GCG codes for Alanine, GGG for Glycine. Wait, but the option says "genotypic because amino acid changed" – but genotypic is about DNA, but maybe the reasoning here: Genotype change (DNA) leads to possible phenotype change (amino acid). Wait, no, let's re - evaluate options:
• Option 2: "phenotypic because change in DNA" – No, phenotype is not DNA sequence change, it's trait.
• Option 3: "genotypic because it is in a gamete" – Genotype is about genetic makeup, not just gamete.
• Option 4: "phenotypic because amino acid changed" – Phenotype is observable trait, not just amino acid change (though amino acid change can lead to phenotype). But the first option: The mutation is in DNA (genotype), and if the amino acid changed (which it does, GCG→GGG: Ala→Gly), then the genotypic change (DNA) causes a change in the gene's product (amino acid), which is part of the genotype - phenotype relationship. Wait, maybe the key is: Genotype is the genetic (DNA) change. The first option says "genotypic because the amino acid changed" – actually, the DNA change (genotype) leads to amino acid change (which can lead to phenotype). But among the options, the correct reasoning is: Genotype is the genetic constitution (DNA sequence). The mutation is a change in DNA (genotype). The first option: "This mutation is genotypic because the amino acid changed" – even though the wording is a bit off (genotype is DNA, but the change in DNA (genotype) causes amino acid change). The other options are wrong: Option 2: Phenotype is not DNA change. Option 3: Genotype not defined by being in gamete. Option 4: Phenotype is not just amino acid change (it's the observable trait, though amino acid change can cause phenotype, but the mutation itself in DNA is genotypic). So the correct option is the first one: "This mutation is genotypic because the amino acid changed".

Answer:

The correct option is: "This mutation is genotypic because the amino acid changed" (assuming this is option A, if we consider the first radio button option as A). If we need to present with the option's text as per the question's options (assuming the first option is the correct one): The option "This mutation is genotypic because the amino acid changed" (the first option in the list of radio buttons).