Question

a patient with a bsa of 0.59 m2 is prescribed mitomycin. the recommended dosages range of this medication is 10 to 20 mg/m2/day. what is the total daily dosage range for this patient?
a) 2.4 mg/day to 5.4 mg/day
b) 7.3 mg/day to 13.6 mg/day
c) 11.8 mg/day to 23.6 mg/day
d) 5.9 mg/day to 11.8 mg/day

Explanation:

Step1: Calculate the lower - bound of the dosage

Multiply the lower - bound of the dosage per square meter (\(10\space mg/m^{2}/day\)) by the patient's BSA (\(0.59\space m^{2}\)).
\(10\times0.59 = 5.9\space mg/day\)

Step2: Calculate the upper - bound of the dosage

Multiply the upper - bound of the dosage per square meter (\(20\space mg/m^{2}/day\)) by the patient's BSA (\(0.59\space m^{2}\)).
\(20\times0.59=11.8\space mg/day\)

Answer:

d) \(5.9\space mg/day\) to \(11.8\space mg/day\)