Question

a nurse is caring for a client who is taking filgrastim to treat neutropenia. the nurse should assess the client for which of the following adverse effects?

• dusky nail beds
• petechiae
• enlarged spleen
• swollen calf

Explanation:

Filgrastim (a granulocyte - colony stimulating factor) can cause splenomegaly (enlarged spleen) as an adverse effect due to increased hematopoietic activity. Dusty nail beds are related to poor perfusion (e.g., in cardiovascular issues), petechiae are due to bleeding disorders or vascular issues (not typical with filgrastim), and a swollen calf suggests DVT (unrelated to filgrastim's main adverse effects on the hematopoietic system and spleen).

Answer:

C. Enlarged spleen