Question

nucleoside triphosphate
nucleotides are added to a growing dna strand as nucleoside triphosphates. what is the significance of this fact?
nucleoside triphosphates are more abundant in the cell than nucleotides.
nucleoside triphosphates are more easily transported in the cell than are nucleotides.
hydrolysis of the two phosphate groups (p - p₁) and dna polymerization are a coupled exergonic reaction.

Explanation:

• Nucleoside triphosphates (NTPs) have high - energy phosphate bonds. When nucleotides are added to the DNA strand as NTPs, the hydrolysis of the two terminal phosphate groups (forming \(PP_i\)) releases energy. This energy is used to drive the endergonic reaction of DNA polymerization (forming phosphodiester bonds in the DNA strand).
• Regarding the first option, nucleotides are actually more abundant in the cell in some contexts (as they are the basic building blocks in terms of simple nucleotide pools).
• For the second option, there is no general rule that nucleoside triphosphates are more easily transported than nucleotides. Nucleotides can also be transported through various cellular mechanisms.

Answer:

Hydrolysis of the two phosphate groups (\(P - P_i\)) and DNA polymerization are a coupled exergonic reaction.