Question

lasix is a diuretic that blocks the reabsorption of sodium in the ascending loop of henle. the result of giving this drug would be
multiple choice
increased urine output
decreased aldosterone production
decreased osmolality of the filtrate
increased osmolality of the urine
decreased urine volume

Explanation:

Lasix, as a diuretic, functions by blocking sodium reabsorption in the ascending loop of Henle. Sodium reabsorption is crucial for water reabsorption in the kidneys. When sodium reabsorption is blocked, less water is reabsorbed back into the bloodstream. This leads to more water remaining in the filtrate, which ultimately results in increased urine output.

• Aldosterone production is regulated by the renin - angiotensin - aldosterone system (RAAS) and is not directly affected by Lasix's action on the loop of Henle.
• Blocking sodium reabsorption in the ascending loop of Henle would increase (not decrease) the osmolality of the filtrate in that segment initially, but overall, the main effect is on urine volume.
• Since more water is not reabsorbed (due to sodium reabsorption block), urine volume increases (not decreases), and the osmolality of the urine would tend to be lower (as more water is excreted) rather than higher.

Answer:

increased urine output