Question

the healthcare provider prescribes naproxen twice daily for a client with osteoarthritis of the hands. the client tells the nurse the drug does not seem to be effective after three weeks. which is the best response for the nurse to provide?
a another type of nonsteroidal antiinflammatory drug may be indicated.
b therapeutic blood levels of this drug are reached in 4 to 6 weeks.
c systemic corticosteroids are the next drugs of choice for pain relief.
d the frequency of the dosing is necessary to increase the effectiveness.

Explanation:

1. Option A is incorrect because the client has only been on the medication for 3 weeks, it is too early to switch medications.
2. Option B is correct: Naproxen, a NSAID for osteoarthritis, typically takes 4 to 6 weeks to reach full therapeutic blood levels and maximum effectiveness. The client has only used it for 3 weeks, so the nurse should explain this timeline.
3. Option C is incorrect because systemic corticosteroids are not the first-line next step; they have significant side effects and are reserved for more severe, refractory cases after other NSAIDs or treatments are attempted.
4. Option D is incorrect because increasing dosing frequency without provider approval is unsafe, as it increases the risk of adverse effects like GI bleeding or renal damage, and the client has not yet reached the drug's full therapeutic window.

Answer:

B Therapeutic blood levels of this drug are reached in 4 to 6 weeks.