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a decrease in heart rate and blood pressure results when drugs such as propranolol block or inhibit receptors in the heart.
Brief Explanations
Propranolol is a beta - blocker. Beta - adrenergic receptors ($\beta$ - receptors) in the heart, when stimulated, increase heart rate and contractility. When these receptors are blocked (by drugs like propranolol), the heart rate and blood pressure decrease.
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$\beta$ - adrenergic