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besides the ability of some cancer cells to divide uncontrollably, what…

Question

besides the ability of some cancer cells to divide uncontrollably, what else might logically result in the formation of a tumor?
changes in the order of cell cycle stages
inability to form spindles
lack of appropriate cell death
enhanced anchorage dependence

Explanation:

Brief Explanations

Cancer cells divide uncontrollably. Tumor formation also relates to cell death regulation. Apoptosis (programmed cell death) is disrupted in cancer. If cells don't die appropriately (lack of apoptosis), excess cells accumulate, forming a tumor. Cell - cycle stage order changes don't directly cause tumors. Inability to form spindles would disrupt mitosis (but cancer cells often have abnormal mitosis, but spindle formation is not the key here). Enhanced anchorage dependence is opposite to cancer cell behavior (cancer cells have reduced anchorage dependence).

Answer:

lack of appropriate cell death