Question

30 multiple choice 1 point
which of the following statements is true about hnpcc, hereditary non - polyposis colorectal cancer?
it causes cancer in all individuals who inherits this mutation
it is a cancer passed from one generation to the next
it is a cancer caused by uv - b
individuals receiving an hnpcc mutation are predisposed to high risk of this cancer

Explanation:

• First option: Not all with the mutation get cancer (incomplete penetrance), so false.
• Second option: HNPCC is a genetic predisposition, not the cancer itself passed down, so false.
• Third option: UV - B causes skin - related cancers, not HNPCC, so false.
• Fourth option: HNPCC mutation carriers have a high predisposition (increased risk) for colorectal cancer, which is true.

Answer:

D. Individuals receiving an HNPCC mutation are predisposed to high risk of this cancer