QUESTION IMAGE
Question
- which stage of action potential comes when an impulse arrives at the axon?
- what does the impulse cause during depolarization?
- when the na+ channels open during depolarization, what happens to sodium?
- what does this rush in of na+ cause?
- once na+ rushes in and is at equilibrium (ex. 4 inside, 4 outside) is there a concentration gradient of na+ anymore?
- if there is no concentration gradient, what happens to the sodium voltage - gated channels?
- after depolarization, which stage of action potential comes next?
- what happens at the beginning of repolarization?
- when the k+ channels open, what happens to potassium?
- what does this rush out of k+ cause?
Brief Explanations
These questions are about the action potential in neurons, which is a topic in Biology (a subfield of Natural Science). Let's answer each:
- When an impulse arrives at the axon, the first stage of action potential is Depolarization. The arrival of the impulse triggers the opening of voltage - gated sodium channels.
- During depolarization, the impulse causes voltage - gated sodium channels to open. This is the initial event that starts the change in membrane potential.
- When Na⁺ channels open during depolarization, sodium (Na⁺) rushes into the neuron (from the extracellular fluid to the intracellular fluid). This is because there is a higher concentration of Na⁺ outside the neuron and the channels are now open, allowing diffusion down the concentration gradient.
- The rush in of Na⁺ causes the membrane potential to become more positive (depolarization). The influx of positive Na⁺ ions makes the inside of the neuron less negative (or even positive) compared to the resting state.
- If Na⁺ is at equilibrium (equal concentration inside and outside, like 4 inside and 4 outside), there is no concentration gradient for Na⁺ anymore. A concentration gradient exists when there is a difference in concentration between two areas; if they are equal, the gradient is zero.
- If there is no concentration gradient, the sodium voltage - gated channels close (inactivate). Once the concentration gradient is gone, these channels stop allowing Na⁺ to pass, and they enter an inactivated state during the action potential process.
- After depolarization, the next stage of action potential is Repolarization. After the sodium channels inactivate, potassium channels start to open, leading to repolarization.
- At the beginning of repolarization, voltage - gated potassium channels open. This allows potassium (K⁺) to move out of the neuron, starting the process of restoring the negative membrane potential.
- When K⁺ channels open, potassium (K⁺) rushes out of the neuron (from the intracellular fluid to the extracellular fluid). There is a higher concentration of K⁺ inside the neuron at rest, so when the channels open, K⁺ diffuses down its concentration gradient.
- The rush out of K⁺ causes the membrane potential to become more negative (repolarization, and eventually hyperpolarization in some cases). The loss of positive K⁺ ions from the inside of the neuron makes the membrane potential more negative, moving back towards (or beyond) the resting membrane potential.
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- Depolarization
- Voltage - gated sodium channels to open
- Sodium rushes into the neuron
- The membrane potential to become more positive (depolarization)
- No
- The sodium voltage - gated channels close (inactivate)
- Repolarization
- Voltage - gated potassium channels open
- Potassium rushes out of the neuron
- The membrane potential to become more negative (repolarization/hyperpolarization)